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Moreover, LRP1 is strongly associated to IR because it is involved in the insulin receptor trafficking and intracellular signaling, as well as in glucose uptake in several tissues, but mainly in the brain ( Both the nuclear receptors PPARγ and LXRs are also implicated in the regulation of lipid metabolism

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10.3803/EnM.2022.1604 [DOI] [PMC free article] [PubMed] [Google Scholar] Chen K., Jiang X., Wu M., Cao X., Bao W., Zhu L.-Q

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